Nucleotide Market size – USD 550.10 Million in 2021, Growth – CAGR of 5.9%, Trends – Increasing use of next-generation sequencing methods for studying viral pathogens

Rising demand for nucleotides in the Food & Beverage (F&B) industry and increasing demand for dietary nucleotides are some major factors driving market revenue growth 

The global Nucleotide Market size is expected to reach USD 926.18 Million in 2030 and register a revenue CAGR of 5.9%, according to the latest report by Reports and Data. Key factors, such as rising demand for nucleotides in the Food & Beverage (F&B) industry and increasing demand for dietary nucleotides are driving global market revenue growth. 

In addition, increasing nucleotide application in various end-use industries such as pharmaceuticals, food & beverage additives, animal feed additives, and diagnostic testing is driving revenue growth of the market. Growing customer consciousness of adverse effects of savory ingredients is estimated to spur demand for a nucleotide-based flavoring agent. Moreover, advancements in methods is another factor anticipated to foster market revenue growth during the forecast period. Nucleotides are synthesized endogenously and have important effects on growth and development of cells with a high turnover rate such as those in the immune system and digestive tract. Nucleoproteins and nucleic acids, which are present in various amounts in many foods, such as lamb, liver, and mushrooms, are dietary sources of nucleotides. Furthermore, increasing demand for nucleotide-rich food items will drive revenue growth of the market between 2022 and 2030.

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Top Companies: Geneaid Biotech Ltd., MCLAB, ProMega Corporation, PurMaBiologics, QIAGEN, Takara Bio, Inc., Thermo Fisher Scientific, TransGen Biotech Co., Ltd., PolyOrg, Inc., Zymo Research Corporation, Trilink Biotechnologies, Inc., Meridian Bioscience, LGC Biosearch Technologies, BOC Sciences, Ajinomoto Co., Inc., Merck KGaA, PerkinElmer, Inc., and Jena Bioscience GmbH. 

Further Key Finding from the Report Suggestion:

·         Based on technology, the TaqMan Allelic Discrimination segment was valued at USD 206.23 Million in 2021 and is expected to be valued at USD 325.37 Million by 2030, growing at a CAGR of 5.1% during the forecast period. Allelic discrimination assays are widely used in academic and research laboratories for genotyping frame shifts, point mutations, as well as small (six base pair length) insertions and deletions. TaqMan allelic discrimination assays use a TaqMan probe for detecting specific alleles in Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) samples. The assay enables researchers to rapidly detect allelic variations observed in samples of patients with genetic disorders. Furthermore, rising prevalence of viral diseases is expected to further increase demand of this assay, thereby driving revenue growth of this segment during the forecast period.

·         Based on application, the molecular biology segment is projected to account for a significant revenue share over the forecast period. Diagnostics and treatment of human diseases have been facilitated by genomic technology developments. In genetics, introduction of molecular technology has led to development of novel approaches for diagnostic and predictive DNA analysis that are increasingly specific, quick, and trustworthy. In addition, production of nucleic acid analogues has become an important aspect of modern biology, due to potential application of these new biomarkers in genetic diagnosis and research. In the past decade, nucleic acids have been widely changed by substituting neutral or charged structures for phosphodiester linker or sugar-phosphodiester backbone. Several of these modified oligonucleotides exhibit enhanced Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) affinity and binding characteristics. Locked Nucleic Acids (LNAs), also known as Bridging Nucleic Acids (BNAs) and Peptide Nucleic Acids (PNAs) are two prominent representations of this new form of oligomers.

Market Overview:

Consumers are placing a higher importance on sustainability and, as a result, are choosing items based on factors like circularity and carbon footprint. Furthermore, consumer concern about carbon emissions has prompted increased investment in renewable energy, energy efficiency, and transportation decarbonization. These developments have had considerable impact on chemical end sectors, particularly in the automobile and construction industries. COVID-19 has exacerbated the situation by lowering the automobile and construction industries (as well as many others) and disrupting current supply lines.

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The global Nucleotide Market is segmented into:

Product Outlook (Revenue, USD Million, 2019 - 2030)

·         Laboratory Grade

o    Deoxynucleotide Triphosphates (dNTPs)

§  Deoxyadenosine Triphosphate (dATP)

§  Deoxycytidine Triphosphate (dCTP)

§  Deoxyguanosine Triphosphate (dGTP)

§  Thymidine Triphosphate (dTTP)

o    Nucleoside Triphosphates (NTPs)

§  Adenosine Triphosphate (ATP)

§  Tetrahydrogen Triphosphate (CTP)

§  Guanosine-5’-Triphosphate (GTP)

§  Uridine Triphosphate (UTP)

o    Modified Nucleotides

§  Fluorescently-labeled Nucleotides

§  Biotin-labeled Nucleotides

§  Linker-modified Nucleotides

§  Cap Analog and Variants

o    Industry Grade

o    Food Grade

Concentration Outlook (Revenue, USD Million, 2019 - 2030)

·         2-5 mM

·         5-10 mM

·         10-25 mM

·         25-100 mM

Technology Outlook (Revenue, USD Million, 2019 - 2030)

·         TaqMan Allelic Discrimination

·         Gene Chips & Microarrays

·         SNP by Pyrosequencing

·         Other Technologies

Application Outlook (Revenue, USD Million, 2019 - 2030)

·         Pharmaceutical Research

·         Diagnostic Application

·         Molecular Biology

o    PCR

§  Reverse Transcriptase

§  DNA Labeling

§  Other Molecular Biology

o    Food and Beverage Additive

o    Animal Feed Additive

o    Other Applications

End-User Outlook (Revenue, USD Million, 2019 - 2030)

·         Pharmaceutical and Biotechnology Companies

·         Diagnostic Labs

·         Academic and Research Institutes

·         Other End-users

Regional Outlook:

·         North America (U.S.A., Canada, Mexico)

·         Europe (Italy, U.K., Germany, France, Rest of Europe)

·         Asia Pacific (China, India, Japan, South Korea, Australia, Rest of APAC)

·         Latin America (Chile, Brazil, Argentina, Peru, Rest of Latin America)

·         Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of MEA)

Key Questions Addressed in the Report:

  • What are the dominating factors that are influencing the growth of the industry?
  • In the forecast period, which market segment is expected to rise the most?
  • What are the risks and challenges that the industry is facing?
  • In the coming years, which area is projected to dominate the market?
  • Who are the major players in the market?
  • What kind of strategic business plans have they made?

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